Mikaela Laine

Mikaela Laine has a special interest in the neurobiology of psychological phenomena, and a passion for education. She acquired her undergraduate degree in Psychology and was keen to better understand the intersections of psychology and neuroscience across species. During her doctoral and post-doctoral work she investigated how individual differences, such as genetic factors and sex, affect responses to stressful experiences at the level of the brain and behavior. Outside academia she is an avid crafter and dog-owner.

Selected Publications 

Laine MA, Greiner EM, Shansky RM (2024). Sex differences in the rodent medial prefrontal cortex - What Do and Don't we know? Neuropharmacology, doi: 10.1016/j.neuropharm.2024.109867

Huckleberry K, Calitri R, Li A, Mejdell M, Singh A, Bhutani V, Laine MA, … , Shansky RM (2023). CB1Rblockade unmasks TRPV1-mediated contextual fear generalization in female, but not male rats.Neuropsychopharmacology, doi: 10.1038/s41386-023-01650-z

Koskinen M-K*, Laine MA*, Abdollahzadeh A, Gigliotta A, Mazzini G, Journée SH, … , & Hovatt a I (2023).Node of Ranvier remodeling in chronic psychosocial stress and anxiety. Neuropsychopharmacology, doi:10.1038/s41386-023-01568-6

Laine MA, Mitchell JR, Rhyner, J, Clark R, Kannan A, Keith J, Pikus M, Bergeron E, Ravaglia I, Ulgenturk E,Shinde A, & Shansky RM (2022). Sounding the alarm: sex differences in rat ultrasonic vocalizations during Pavlovian fear conditioning and extinction. eNeuro, 9(6), doi:10.1523/ENEURO.0382-22.2022

Mitchell JR, Trett el S, Li A, … , Laine MA, & Shansky RM (2022). Darting across space and time: Parametricmodulators of sex-biased conditioned fear responses. Learning and Memory, 29, 171-180, doi:10.1101/lm.053587.122

Laine MA & Shansky RM (2022). Rodent models of stress and dendritic plasticity – implications for psychopathology. Neurobiology of Stress, 17(Special Issue commemorating Dr Bruce McEwen). doi:10.1016/j.ynstr.2022.100438

Meier SM, Trontti K, Purves KL, … ,Laine, MA, … , & Mors O (2019). Genetic Variants Associated With Anxiety and Stress-Related Disorders - A Genome-Wide Association Study and Mouse-Model Study. JAMAPsychiatry, 76(9), 924-932. doi: 10.1001/jamapsychiatry.2019.1119

Misiewicz Z, Iurato S, Kulesskaya N, … ,Laine MA, … , & Hovatta I (2019). Multi -omics analysis identifies mitochondrial pathways associated with anxiety-related behavior. PLoS Genetics, 15(9). doi:10.1371/journal.pgen.1008358

Laine MA*, Trontti K*, Misiewicz Z*, Sokolowska E*, Kulesskaya N, Heikkinen A, … , & Hovatt a I (2018). Genetic control of myelin plasticity after chronic psychosocial stress. eNeuro, 5(4). doi:10.1523/ENEURO.0166-18.2018

Laine MA, Sokolowska E, Dudek M, Callan SA, Hyytiä P, Hovatta I (2017). Brain activation induced by chronic psychosocial stress in mice. Scientific Reports, 7, 15061, doi:10.1038/s41598-017-15422-5